How to estimate the exposure to the ingredients of food packaging – Part I

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How-to-estimate-the-exposure-to-the-ingredients-of-food-packaging-Part-I

The primary objective of doing leaching studies is to evaluate the exposure of food packaging ingredients. Exposure is measured to determine an estimation of daily intake (EDI). The EDI for a particular migrant is matched with the acceptable daily intake (ADI) of the migrant, as determined by FDA toxicologists.
An estimate of the exposure to an additive in the diet is found by consolidating migration data from food simulants or actual foods with information on the uses of food packaging that may comprise the additive.
This information includes food type concentration factors, and the fraction of the daily diet expected to contact specific packaging materials, i.e., consumption factors (CF). Consumption factors are obtained by using information on U.S. food packaging markets to calculate the fraction of the diet likely to contact broad categories of food packaging (i.e., glass, metal, plastic, paper) as well as specific types of food-contact polymers.

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